Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-07-19
2005-07-19
Kim, Vickie (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S375000, C548S309700, C548S310100, C548S310700
Reexamination Certificate
active
06919366
ABSTRACT:
This invention relates to a family of benzimidazole analogs, which are inhibitors of the IgE response to allergens. These compounds are useful in the treatment of allergy, asthma, or any diseases where IgE is pathogenic.
REFERENCES:
patent: 6153631 (2000-11-01), Petrie et al.
patent: 6387938 (2002-05-01), Mizuguchi et al.
patent: 0 221 146 (1987-05-01), None
patent: 0 221 346 (1987-05-01), None
patent: 0 232 199 (1987-08-01), None
patent: 0 232 199 (1989-08-01), None
patent: 0 469 477 (1992-02-01), None
patent: 0 497 564 (1992-08-01), None
patent: 0 700 906 (1996-03-01), None
patent: 719765 (1996-03-01), None
patent: 0 719 765 (1996-07-01), None
patent: WO 90 09989 (1990-09-01), None
patent: WO 93 25517 (1993-12-01), None
patent: WO 98 17267 (1998-04-01), None
patent: WO 9961019 (1999-02-01), None
patent: WO 99 610020 (1999-02-01), None
patent: WO 8906975 (1999-08-01), None
patent: WO 0026192 (2000-05-01), None
patent: WO 0029384 (2000-05-01), None
Pozdnyakov et al. “Mass Spectrometric study of dissociative ionization of low-molecular models of aromatic polyamides” Khim. Vys. Energ. (1987), 21(1), 38-44 Coden: Khvkao; ISSN: 0023-1193, 1987.
S. Karag'ozov, Synthesis of N-acyl derivatives of 6-amino-1-4-benzodioxane STN International, vol. 39, No. 1989 pp. 5-8, Abstract only.
Ashton et al., “Now low-density lipoprotein receptor upregulatros acting via a novel mechanism”, Journal of Medicinal Chemistry, vol. 39, Jan. 1, 1996, pp. 3343-3356.
B.V. Cheney et al., “Structure-activity correlations for a series of antiallergy agents. 3. Development of a quantitative model”, Journal Med. Chem, vol. 26, No. 5, 1983, pp. 726-737.
I Yildir, “Synthesis of 2-(substitutedphenyl) benzimidazole derivatives and their sedative activity: Structure-activity relationship”, Journal Fax. Gazi Uni., vol. 7, No. 2 1990, pp. 111-114.
Japanese Application No. 10273013, entitled Antagonist for Gonadotrophic Hormone-Releasing Hormone, filed on Sep. 28, 1998, English abstract only.
Database Crossifre Beilstein 'Onlinel, Beilstein Institut zur Forderung der Chemischen Wissenchaften, Frankfurt am Main, DE; Beilstein Registry No. 563073 & Khim, Farm. ZH., vol. 22, No. 6, 1988, pp. 697-699.
Denny W A et al., Potential antitumor agents. 59. Structure-activity relationships for 2-phenyibenzimidazole-4-carboxamides, a new class of “minimal” DNA-intercalating agents which may not act via topoisomerase II, Journal of Medicinal Chemistry, vol. 33, No. 2, Feb. 1990, pp. 814-819.
White A W et al., “Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase”, Journal of Medicinal Chemistry, vol. 43, No. 2, Nov. 2, 2000, pp. 4084-4097.
Database Caplus 'Onlinel Chemical Abstracts Service, Columbus, Ohio, US; Databse accession no. 2000:214835 & JP 2000 095767 (Takeda Chemical Industries, Ltd.), Apr. 4, 2000.
Kreimeyer A et al., “Suramin analogues with a 2-phenylbenzimidazole moiety as partyial structure; potential anti HIV- and angiostic drugs, 2: Sulfanilic acid, benzendisulfonic, and naphthalenetrisulfonic acid analogues” Archi Der Pharmazie, vol. 331, No. 3, Mar. 1998, pp. 97-103.
S. Karag'ozov, “Synthesis of N-acyl derivatives of 6-amino-1-4-benzodioxane”, Stn International, vol. 39, 1989, pp. 5-8, Abstract only.
Ashton et al., “New low-density lipoprotein receptor uregulators acting via a novel mechanism”, Journal of Medicinal Chemistry, vol. 39, pp. 3343-3356. 1996.
B.V. Cheney et al., “Structure-activity correlations for a series of antiallergy agents; development of a quantitative model”, Journal of Medicinal Chemistry, vol. 26, No. 5, pp. 726-737, 1983.
I. Yildir, “Synthesis of 2-(Substitutedphenyl) benzimidazole derivatives and their sedative activity: Structure-activity relationship,” Journal Fax. Gazi Uni., vol. 7, No. 2, pp. 111-114. 1990.
Campbell Michael G.
Major Michael W.
Richards Mark L.
Sircar Jagadish C.
Avanir Pharmaceuticals
Kim Vickie
Knobbe Martens Olson & Bear LLP
LandOfFree
Benzimidazole derivatives as modulators of IgE does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzimidazole derivatives as modulators of IgE, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzimidazole derivatives as modulators of IgE will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3398320