Benzimidazole derivatives and their use as GnRH antagonists

Details Benzimidazole derivatives and their use as GnRH antagonists Benzimidazole derivatives and their use as GnRH antagonists

2002-12-20

2009-02-24

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S307400

Reexamination Certificate

active

07495110

ABSTRACT:
A subject of the present application is new benzimidazole derivatives of formulain which A, Y, R1, R2, R3and R4represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.

REFERENCES:
patent: 6825219 (2004-11-01), Cywin et al.
patent: 7132438 (2006-11-01), Frenkel et al.
patent: WO 97/21435 (1997-06-01), None
Golub et al., Science, vol. 286, Oct. 15, 1999, pp. 531-537.
Database WPI, Section Ch, Week 200030, Derwent Publications Ltd., London, GB; AN 2000-342515 XP-002210484 & JP 2000 095767, (Takeda Chem Ind Ltd), Apr. 4, 2000 AB.

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