Benzimidazole derivatives

Details Benzimidazole derivatives Benzimidazole derivatives

2005-11-29

2005-11-29

McKenzie, Thomas C. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S253040, C514S254060, C514S249000, C514S303000, C514S395000, C540S575000, C544S350000, C544S362000, C546S118000, C548S306100

Reexamination Certificate

active

06969712

ABSTRACT:
This invention relates to the compounds represented by a general formula [I]:[in which A1and A2represent optionally fluorine-substituted methine or the like; B represents halogen, cyano, lower alkyl or the like; D represents optionally substituted heterocyclic group or the like; and G represents C3-C20aliphatic group such as alicyclic group]. These compounds inhibit nociceptin activities due to their high affinity to nociceptin receptor, and are useful as analgesic, antiobestic, corebral function improver, drugs for treatment of alzheimer's disease and dementia, remedies for schizophrenia and neurodegenerative diseases, antidepressant, remedies for diabetes insipidus, polyuria, hypotension and so on.

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