Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1991-09-30
1994-05-24
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514338, 514381, 514382, 514394, 514395, 514365, 548113, 548181, 548252, 548253, 548254, 5483021, 5483044, 5483077, 5483064, 5483071, 5483097, 5483101, 5483104, 546 22, 546271, A61K 31415, A61K 3144, C07D23504, C07D41712
Patent
active
053148800
ABSTRACT:
Compounds of general formula I: ##STR1## wherein: each of R.sup.1 -R.sup.8, k, and V represent disclosed functional groups that have been chosen such that all disclosed variations of compound I and their pharmaceutically and veterinarily acceptable acid addition salts and hydrates are antagonists of platelet activating factor (PAF) and as such are useful in the treatment or amelioration of various diseases or disorders mediated by PAF.
REFERENCES:
patent: 3317554 (1967-05-01), Goldsmith et al.
Kishida et al., Chem. Abstr., vol. 106, No. 3; 18545y (1987).
Hirosi et al., Chem. Abstr., vol. 102, No. 19; 166754y (1985).
Kisida et al., Chem. Abstr., vol. 104, No. 21; 186419n (1986).
Kisida et al., Chem. Abstr., vol. 105, No. 15; 133889e (1986).
Davidson Alan H.
Dickens Jonathan P.
Floyd Christopher D.
Whittaker Mark
British Bio-technology Limited
Richter Johann
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