Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-02-10
1988-06-28
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546271, C07D40112, A61K 3144
Patent
active
047539550
ABSTRACT:
Benzimidazole derivatives of the general formula [I] are provided: ##STR1## wherein R.sup.1 is hydrogen, methyl or methoxy, and R.sup.2 and R.sup.3 each is hydrogen or methyl, at least one of R.sup.1, R.sup.2 and R.sup.3 being a member other than hydrogen. The benzimidazole derivatives exhibit an excellent activity of inhibiting the potassium ion-dependent adenosine triphosphatase, as well as a good stability during storage. Therefore, the benzimidazole derivatives are usable for the treatment of gastric and/or duodenal ulcers.
REFERENCES:
patent: 4472409 (1984-09-01), Senn-Bilfinger
Hisamitsu Akira
Iizumi Kenichi
Matsuishi Naoto
Murakami Kiyokazu
Takeda Haruki
Fan Jane T.
Tokyo Tanabe Company Ltd.
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