Benzimidazole derivative

Details Benzimidazole derivative Benzimidazole derivative

2007-02-13

2007-02-13

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S387000

Reexamination Certificate

active

10777067

ABSTRACT:
A benzimidazole derivative or its medically acceptable salt, represented by the following formula (1), that is a human chymase activity inhibitor capable of being applied clinically:wherein, R1and R2represent a hydrogen atom, an alkyl group or an alkoxy group, etc., A represents an alkylene group or an alkenylene group, E represents —COOR3, —SO3R3, —CONHR3or —SO2NHR3, etc., G represents an alkylene group, M represents a single bond or —S(O)m—, J represents a heterocyclic group, and X represents —CH═ or a nitrogen atom.

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Golub et al., Science, vol. 286, Oct. 15, 1999, pp. 531-537.

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