Benzimidazole compounds having nociceptin receptor affinity

Details Benzimidazole compounds having nociceptin receptor affinity Benzimidazole compounds having nociceptin receptor affinity

2000-12-06

2008-11-25

Andres, Janet L. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S199000

Reexamination Certificate

active

07456198

ABSTRACT:
Disclosed are compounds of the formula (I)wherein A, R1, R2, R3, R4and X1are as disclosed herein. The compounds have affinity for the ORL1 receptor and are useful in the treatment of chronic and acute pain.

REFERENCES:
patent: 3161645 (1964-12-01), Adrian et al.
patent: 3196157 (1965-07-01), Janssen et al.
patent: 3318900 (1967-05-01), Adrian et al.
patent: 4329353 (1982-05-01), Stokbroekx et al.
patent: 2006/0264638 (2006-11-01), Kyle et al.
patent: 0008259 (1980-02-01), None
patent: 0092391 (1983-10-01), None
patent: 0921125 (1999-06-01), None
patent: 9710213 (1997-03-01), None
patent: 9740035 (1997-10-01), None
patent: 9854168 (1998-12-01), None
patent: 9929696 (1999-06-01), None
patent: 9936421 (1999-06-01), None
patent: 9948492 (1999-09-01), None
patent: 9959997 (1999-11-01), None
patent: 0006545 (2000-02-01), None
Hcaplus 129:290436.
Hcaplus 130:52418.
Obase, et al., “New Antihypertensive Agents. I. Synthesis and Antihypertensive Activity of Some 4-Piperidylbensimidasolinone Derivatives”, Chemical Pharmaceutical Bulletin, vol. 30, pp. 462-473, 1982.

Affiliated with

Also associated with

Rating

Benzimidazole compounds having nociceptin receptor affinity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzimidazole compounds having nociceptin receptor affinity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzimidazole compounds having nociceptin receptor affinity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4043596