Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-10-16
2007-10-16
Desai, Rita (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S268100
Reexamination Certificate
active
10795006
ABSTRACT:
The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to benzimidazole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents.
REFERENCES:
patent: 4510158 (1985-04-01), Bailey
patent: 4582837 (1986-04-01), Hauel et al.
patent: 4696931 (1987-09-01), Hauel et al.
patent: 5017467 (1991-05-01), Masukawa et al.
patent: 5124336 (1992-06-01), Bru-Magniez et al.
patent: 5322847 (1994-06-01), Marfat et al.
patent: 5380865 (1995-01-01), Cramp et al.
patent: 5643893 (1997-07-01), Benson et al.
patent: 5712392 (1998-01-01), Thurkauf et al.
patent: 5821258 (1998-10-01), Matsunaga et al.
patent: 5935983 (1999-08-01), Muller-Gliemann et al.
patent: 6093728 (2000-07-01), McMahon et al.
patent: 6100282 (2000-08-01), Alig et al.
patent: 6100283 (2000-08-01), Griffin et al.
patent: 6153631 (2000-11-01), Petrie et al.
patent: 6271249 (2001-08-01), Romine et al.
patent: 6271390 (2001-08-01), Sircar et al.
patent: 6288101 (2001-09-01), Glennon
patent: 6303645 (2001-10-01), Sircar et al.
patent: 6369091 (2002-04-01), Sircar et al.
patent: 6387938 (2002-05-01), Mizuguchi et al.
patent: 6451829 (2002-09-01), Sircar et al.
patent: 6486153 (2002-11-01), Castro Pineiro et al.
patent: 6503938 (2003-01-01), Von Angerer et al.
patent: 6509365 (2003-01-01), Lubisch et al.
patent: 6537994 (2003-03-01), Ashwell et al.
patent: 6759425 (2004-07-01), Sircar et al.
patent: 6911462 (2005-06-01), Sircar et al.
patent: 6919366 (2005-07-01), Sircar et al.
patent: 2002/0010343 (2002-01-01), Sircar et al.
patent: 2002/0132808 (2002-09-01), Sircar et al.
patent: 2003/0004203 (2003-01-01), Sircar et al.
patent: 2003/0100582 (2003-05-01), Sircar et al.
patent: 2004/0116466 (2004-06-01), Sircar et al.
patent: 2004/0180946 (2004-09-01), Sircar et al.
patent: 2004/0229927 (2004-11-01), Sircar et al.
patent: 2005/0075343 (2005-04-01), Sircar et al.
patent: 2005/0197375 (2005-09-01), Sircar et al.
patent: 2005/0256179 (2005-11-01), Sircar et al.
patent: 2005/0277686 (2005-12-01), Sircar et al.
patent: 0 221 146 (1987-05-01), None
patent: 0 221 346 (1987-05-01), None
patent: 0 232 199 (1987-08-01), None
patent: 0 353 606 (1990-02-01), None
patent: 0 415 886 (1990-08-01), None
patent: 0 385 850 (1990-09-01), None
patent: 0 469 477 (1992-02-01), None
patent: 0 497 564 (1992-05-01), None
patent: 0694535 (1996-01-01), None
patent: 0 700 906 (1996-03-01), None
patent: 719765 (1996-03-01), None
patent: 0 719 765 (1996-07-01), None
patent: 0719 765 (1996-07-01), None
patent: 1 077 700 (2001-02-01), None
patent: 1 123 295 (2001-08-01), None
patent: 1 125 936 (2001-08-01), None
patent: 06 263993 (1994-09-01), None
patent: 1316559 (1983-06-01), None
patent: WO90/09989 (1990-09-01), None
patent: WO92 02500 (1992-02-01), None
patent: WO93/25517 (1993-12-01), None
patent: WO98/17267 (1998-04-01), None
patent: WO98/47890 (1998-10-01), None
patent: WO98/56761 (1998-12-01), None
patent: WO99 61020 (1999-02-01), None
patent: WO9961019 (1999-02-01), None
patent: WO8906975 (1999-08-01), None
patent: WO99 61013 (1999-12-01), None
patent: WO99 61019 (1999-12-01), None
patent: WO99 61020 (1999-12-01), None
patent: WO 00/26192 (2000-05-01), None
patent: WO 00/29384 (2000-05-01), None
patent: WO 0026192 (2000-05-01), None
patent: WO 0029384 (2000-05-01), None
patent: WO 00/32579 (2000-06-01), None
patent: WO 00/64878 (2000-11-01), None
patent: WO 00/68206 (2000-11-01), None
patent: WO 01/12169 (2001-02-01), None
patent: WO 01/14342 (2001-03-01), None
patent: WO 01 14342 (2001-03-01), None
patent: WO 01 72737 (2001-10-01), None
patent: WO 02 72090 (2002-09-01), None
patent: WO 02/072539 (2002-09-01), None
patent: WO 02/072574 (2002-09-01), None
patent: WO 04 024896 (2004-03-01), None
Yildir et al. “Synthesis of 2-(Substitutedphenyl)Benzimidazole Derivatives and Their Sedative Activity: Structure-Activity Relationships”. J. Fac. Pharm. Gazi, vol. 7, No. 2, 1990, pp. 111-124.
Related pending PCT Patent Application No. PCT/US03/05985, filed Feb. 25, 2003. Title: Use of Benzimidazole Analogs in the Treatment of Cell Proliferation. Inventors: Jagadish C. Sircar et al.
Related pending U.S. Appl. No. 10/661,139, filed Sep. 12, 2003. Title: Phenyl-Indole Compounds for Modulating IgE and Inhibiting Cellular Proliferation. Inventors: Jagadish C. Sircar et al.
Related pending U.S. Appl. No. 10/661,296, filed Sep. 12, 2003. Title: Phenyl-Aza-Benzimidazole Compounds for Modulating IgE and Inhibiting Cellular Proliferation. Inventors: Jagadish C. Sircar et al.
Ashton, Michael et al., “New Low-Density Lipoprotein Receptor Upregulators Acting via a Novel Mechanism”, Journal of Medicinal Chemistry vol. 39, pp. 3343-3356, 1996.
Cheney, B. Vernon, “Structure-Activity Correlations for a Series of Antiallergy Agents. 3. Development of a Quantitative Model”, Journal of Medicinal Chemistry vol. 26, pp. 726-737, 1983.
Karag'ozov, S., “Synthesis of N-acyl Derivatives of 6-amino-1-4-benzodioxane”, Farmatsiya vol. 39, No. 2, pp. 5-8, 1989. (Bulgaria).
Pozdnyakov et al., “Mass Spectrometric Study of Dissociative Ionization of Low-Molecular Modules of Aromatice Polyamides”, Khim. Vys. Energ., vol. 21, No. 1, pp. 38-44, 1987. (Russia).
Japanese Application No. 10273013 entitled, Antagonist for Gonadotrophic Hormone-Releasing Hormone, filed on Sep. 28, 1998, English abstract only.
Database Crossfire Beilstein 'Online!, Beilstein Institut zur Forderung der Chemischen Wissenchaften, Frankfurt am Main, DE; Beilstein Registry No. 563073 & Khim. Farm. ZH., vol. 22, No. 6, 1988, pp. 697-699.
Denny W A et al., “Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of “minimal” DNA-intercalating agents which may not act via topoisomerase II”, Journal of Medicinal Chemistry, vol. 33, No. 2, Feb. 1990, pp. 814-819.
White A W et al., “Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase”, Journal of Medicinal Chemistry, vol. 43, No. 2, Nov. 2, 2000, pp. 4084-4097.
Database Caplus 'Online! Chemical Abstracts Service, Columbus, Ohio, US; Database accession No. 2000:214835 & JP 2000 095767 (Takeda Chemical Industries, Ltd.), Apr. 4, 2000.
Kreimeyer A et al., “Suramin analogues with a 2-phenylbenzimidazole moiety as partyial structure; potential anti HIV-and angiostic drugs, 2: Sulfanilic acid, benzendisulfonic, and naphthalenetrisulfonic acid analogues” Archi Der Pharmazie, vol. 331, No. 3, Mar. 1998, pp. 97-103.
Chilean Office Action with Search Report for the Chilean counterpart of the U.S. Appl. No. 10/795,006.
Related pending U.S. Appl. No. 10/821,667, filed Apr. 9, 2004. Title: Imidazole Derivatives for Treatment of Allergic and Hyperproliferative Disorders. Inventors: Jagadish C. Sircar et al.
Related pending U.S. Appl. No. 10/915,722, filed Aug. 9, 2004. Title: Selective Pharmacologic Inhibition of Protein Trafficking and Related Methods of Treating Human Diseases. Inventors: Jagadish C. Sircar et al.
Related pending U.S. Appl. No. 10/508,968, filed Sep. 24, 2004. Title: Use of Benzimidazole Analogs in the Treatment of Cell Proliferation. Inventors: Jagadish C. Sircar et al.
Related pending U.S. Appl. No. 10/951,515, filed Sep. 28, 2004. Title: Benzimidazole Derivatives as Modulators of IgE. Inventors: Jagadish C. Sircar et al.
Related pending U.S. Appl. No.11/168,711, filed Jun. 28, 2005. Title: Benzimidazole Compounds for Regulating IgE. Inventors: Jagadish C. Sircar et al.
Manecke et al., Über Polyamide mit 2,4-Imidazolidiyl-Bausteinen, Die Makromolekulare Chemie 176, pp. 3551-3563 (1975), Apr. 29, 1975, Institut für Organische Chemie der Freien Universität Berline, D-1 Berlin 33.
Cheney B V, et al., “Structure-activity Correlations for a Series of Antiallergy Agents.
Richards Mark L.
Sircar Jagadish C.
Avanir Pharmaceuticals
Knobbe Martens olson & Bear LLP
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