Benzimidazole compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514254, 544 8, 544238, 544239, A61K 3150, C07D40314, C07D40514, C07D41714

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active

054017386

ABSTRACT:
Benzimidazole compounds of the formula I ##STR1## and salts thereof, exhibit antagonistic properties toward angiotensin II and can be used for the treatment of hypertension, aldosteronism, cardiac insufficiency and an increased intraocular pressure, as well as disturbances of the central nervous system.

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Chiu et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 250, No. 3, pp. 867-874 (May 22, 1989).
Wong et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 252, No. 2, pp. 719-725 (Oct. 26, 1989).

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