Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-04-22
1989-09-19
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544397, A61K 31495, C07D29508
Patent
active
048681849
ABSTRACT:
The invention relates to novel benzhydryl-piperazine derivatives of the general formula (I) and the acid addition and quaternary ammonium salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) ##STR1## R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are the same or different and stand for hydrogen or halogen, or a trihalomethyl, C.sub.1-4 alkyl or C.sub.1-4 alkoxy group;
REFERENCES:
patent: 2603435 (1953-03-01), Baltzly et al.
patent: 2709169 (1955-05-01), Morren
patent: 2861072 (1958-11-01), Weston et al.
patent: 2899436 (1959-08-01), Morren
patent: 3178422 (1965-04-01), Cusic et al.
patent: 3652568 (1972-03-01), Winter et al.
patent: 4265894 (1981-05-01), Gootjes
Carlsson, (1988), Perspectives in Psychopharmacology Collection of Papers in Honor of E. Usdin. Alan L. Riss, Inc., pp. 209-223.
Gottries, (1985), Psychopharmacology, 86:245-252.
Morren, N-Monobenzhydrylpiperazines, CA: vol. 53, 18071i-18073c, (1959), eq. BE 523899-523903.
Janssen, Pharmacologically Active Piperazine Derivatives, CA, vol. 54, 2379b, (1960), eq. UK 809760.
UCB, Societe Anon., N-Benzhydrylpiperazine Derivatives, CA, vol. 64, 8207f, (1966), eq. BE 649848.
Nakanishi et al., Piperazine Derivatives, CA, vol. 81, 91580a, (1974), eq. JP 7411713.
Buzas et al., [(Benzhydrloxy)alkyl]piperazines, CA, vol. 88, 62416r, (1978).
Abbott Laboratories, N-Diarylmethylpiperazines, CA, vol. 51, 5847a; 1957.
Walter et al., Unsymmetrically Substituted Piperazines, CA, vol. 53, 21986f-21987f, (1959).
Barrett et al., CA; vol. 57, 13778d, Piperazine Derivatives.
Groo Dora
Hajdu Istvan
Kiss Bela
Lapis Erzsebet
Laszlovszky Istvan
Richter Gedeon Vegyeszeti Gyar
Shen Cecilia
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