Benzhydrylpiperazine derivatives, processes for the preparation

Details Benzhydrylpiperazine derivatives, processes for the preparation Benzhydrylpiperazine derivatives, processes for the preparation

1983-12-21

1986-05-27

Lesmes, George F.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544360, 544368, 544396, 514253, 514255, C07D40112, A61K 31495

Patent

active

045915903

ABSTRACT:
The present invention relates to novel benzhydrylpiperazine derivatives having anti-allergic activities, the preparation of these derivatives, pharmaceutical compositions comprising the same, and to a method of using these compounds therapeutically in the treatment of allergic symptoms in human beings and animals.
These benzhydrylpiperazine derivatives have the follow formula: ##STR1## wherein A is a lower alkylene, Z is a benzhydryl optionally substituted with halogen, and

REFERENCES:
patent: 2861072 (1958-11-01), Weston et al.
patent: 3244718 (1966-04-01), Biel
patent: 4199582 (1980-04-01), Oka et al.
patent: 4243806 (1981-01-01), Raeymaekers et al.
Chemical Abstracts, vol. 82, No. 23, Jun. 9th, 1975, p. 618, No. 156367d, Columbus Ohio (USA).

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