Benzhydrylamine derivatives

Details Benzhydrylamine derivatives Benzhydrylamine derivatives

1989-02-27

1990-10-23

Gray, Bruce

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 27, 562460, C07C22900

Patent

active

049654055

ABSTRACT:
Novel benzhydrylamine derivatives represented by general formulas (I) and (II) are useful as reaction reagents for the solid-phase synthesis of polypeptide amides making use of 9-fluorenylmethyloxycarbonyl group ("Fmoc"). An intermediate for these derivatives represented by the general formula (III) is also disclosed: ##STR1## where R.sub.1 and R.sub.2 each independently represents a C.sub.1 -C.sub.3 lower alkyl; n is an integer of 1-4; l is 1 or 2; and m is 1 or 2.

REFERENCES:
Oe et al., Chemical Abstracts, vol. 81, No. 120462w (1974).

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