Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-07-29
1996-10-15
Haley, Jacqueline
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548484, 548486, A61K 31435, C07D21370
Patent
active
055654843
ABSTRACT:
The invention relates to use of at least one indole derivative of general formula: ##STR1## or of one of the pharmaceutically acceptable salts thereof, in which: Am is selected from radical (a) and (b) defined as follows: ##STR2## R is a C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl radical R.sub.1 represents hydrogen or a C.sub.1 -C.sub.4 alkyl radical
R.sub.2 and R.sub.3, which may be identical or different, represent hydrogen, the methyl or ethyl radical or a halogen
R.sub.4, R.sub.5 and R.sub.6, which may be identical or different, represent hydrogen, a C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy radical or a halogen
R.sub.7 represents hydrogen or a halogen
R.sub.8 represents hydrogen or a C.sub.1 -C.sub.4 alkyl radical
R.sub.9 represents hydrogen or, when R.sub.8 and R.sub.9 are taken together, form the methylene radical
m represents 1 or 2
n represents 2, 3 or 4
for preventing or treating diseases involving a proliferation of smooth muscle cells.
Chatelain Pierre
Herbert Jean-Marc
Haley Jacqueline
Sanofi
LandOfFree
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