Benzenesulphonamide derivatives

Details Benzenesulphonamide derivatives Benzenesulphonamide derivatives

1987-05-11

1988-03-08

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544235, 544293, 544363, 544391, 546160, C07D24104

Patent

active

047300477

ABSTRACT:
Compounds having the formula ##STR1## wherein X.sub.1 and X.sub.2 are independently hydrogen, halogen, trifluoromethyl, lower alkyl or lower alkoxy; X.sub.3 is halogen or trifluoromethyl; one of A and B is CH and the other is CH or N and their pharmaceutically acceptable acid addition salts are useful as pharmaceuticals, in particular as anti-hypertensive agents. Novel 1-[4-(amino or nitro)benzenesulphonyl]-4-benzoylpiperazines are also disclosed as intermediate compounds.

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patent: 4087425 (1978-05-01), Garcia et al.
patent: 4147870 (1979-04-01), Garcia et al.
patent: 4167567 (1979-09-01), McCall
patent: 4425342 (1984-01-01), Allen et al.
Chem. Abst., 76:126526p.

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