Benzenesulfonyl-ureas

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260251R, 2602564R, 2602565R, 260287AR, 260287F, 2602948E, 2602948H, 260304R, 260305, 260307D, 424251, 424258, 424263, 424270, 424272, C07D21538

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active

040255190

ABSTRACT:
Sulfonyl-ureas of the formula ##STR1## wherein X represents a heteroaromatic 5- or 6-ring substituted, if desired, by one or two methyl groups and/or annellated with benzene, which ring may contain in addition to a nitrogen atom a further nitrogen, oxygen or sulfur atom and which, in vicinal position to the nitrogen atom, is linked to the rest of the molecule portion, R is alkyl having 1 to 3 carbon atoms, R.sup.1 is alkyl having 3 to 6 carbon atoms, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, cycloalkenyl, alkylcycloalkenyl having each 5 to 9 carbon atoms, cyclohexenylmethyl, chlorocyclohexyl, bicycloheptenylmethyl, bicycloheptylmethyl, bicycloheptenyl, bicycloheptyl, nortricyclyl, adamantyl, benzyl, which as substance or in form of the salts thereof have hypoglycemic properties and are distinguished by a strong and continuous lowering of the blood sugar level, process for preparing them as well as pharmaceutical preparations containing the sulfonyl-ureas as an active substance.

REFERENCES:
patent: 3655756 (1972-04-01), Weber et al.
patent: 3705151 (1972-12-01), Weber et al.
patent: 3709908 (1973-01-01), Weber et al.
patent: 3751418 (1973-08-01), Weyer et al.
patent: 3813398 (1974-05-01), Aumuller et al.
patent: 3819633 (1974-06-01), Ambrogi et al.
patent: 3887561 (1975-06-01), Evanga et al.

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