Benzenesulfonate salt of 4-fluoro-2-cyanopyrrolidine...

Details Benzenesulfonate salt of 4-fluoro-2-cyanopyrrolidine... Benzenesulfonate salt of 4-fluoro-2-cyanopyrrolidine...

2007-12-04

2007-12-04

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

10525748

ABSTRACT:
A benzenesulfonate salt of (2S,4S)-2-cyano-4-fluoro-1-[(2-hydroxy-1,1-dimethyl)ethylamino]acetylpyrrolidine that has an excellent DPPIV inhibition activity as well as physical properties (e.g., stability) required for pharmaceutical preparations. The present invention allows easy obtaining of the compound in high-purity uniform crystal form with excellent solid-state stability.

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