Benzenesulfonamide derivatives and a process for the medical use

Details Benzenesulfonamide derivatives and a process for the medical use Benzenesulfonamide derivatives and a process for the medical use

1988-04-22

1989-07-18

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548545, C07D20726, A61K 3140

Patent

active

048494445

ABSTRACT:
Compounds of the formula I ##STR1## with R.sup.1 equal to H or (cyclo)alk(en)yl, R.sup.2 equal to H or alkyl, R.sup.3 equal to alkyl, R.sup.4 /R.sup.5 equal to H, alkyl or acyl, and Y equal to H, alkyl, CF.sub.3 or Hal, are described, as are processes for the preparation thereof.
They are effective diuretics and antihypertensive agents with a lipid-lowering action.

REFERENCES:
patent: 4235918 (1980-11-01), Lang et al.

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