Benzene derivatives and pharmaceutical use thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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Details

C564S086000, C564S153000, C564S154000, C564S155000, C564S156000, C564S157000, C564S190000, C562S433000, C560S251000, C558S050000, C558S404000, C548S476000, C548S513000, C546S323000, C514S354000, C514S415000, C514S421000, C514S423000, C514S517000, C514S535000, C514S544000, C514S563000, C514S603000, C514S616000, C514S624000

Reexamination Certificate

active

07459585

ABSTRACT:
The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory cell adhesion molecule expression inhibitor, anti-inflammatory agent, antirheumatic agent, immunosuppressant, cancer metastasis inhibitor, remedy for arteriosclerosis and antiviral agent which contain the benzene derivative of the following general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient.

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V. A. Bren, et al., “Biphotochromic Norbornadiene Systems”, Molecular Crystals and Liquid Crystals, 1997, vol. 297, pp. 247-253.
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