Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2011-04-12
2011-04-12
Puttlitz, Karl J (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C560S064000, C560S065000, C514S717000
Reexamination Certificate
active
07923573
ABSTRACT:
A superior LXR modulator is provided. A compound represented by the general formula (I):[wherein R1: —COR9(wherein R9: alkyl, optionally substituted alkoxy or optionally substituted amino); R2: H, OH, alkoxy, optionally substituted amino, etc.; R3: H, optionally substituted alkyl, cycloalkyl, optionally substituted alkoxy, optionally substituted amino, halogeno, etc.; R4and R5: H, optionally substituted alkyl, halogeno, etc.; R6and R7: H, alkyl; R8: —X2R10[wherein R10: —COR11(wherein R11: OH, optionally substituted alkoxy, optionally substituted amino, etc.), —SO2R12(wherein R12: optionally substituted alkyl, optionally substituted amino, etc.), tetrazol-5-yl, etc.; X2: single bond, optionally substituted alkylene, etc.]; X1: —NH—, —O—, —S—, etc.; Y1: optionally substituted phenyl, optionally substituted 5- to 6-membered aromatic heterocyclyl; Y2: optionally substituted aryl, optionally substituted heterocyclyl, etc.] and the like is provided.
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Nakadai Masakazu
Nakai Daisuke
Oda Kozo
Tamaki Kazuhiko
Terasaka Naoki
Daiichi Sankyo Company, Limited
Locke Lord Bissell & Liddell
Puttlitz Karl J
Schurter Brandon T.
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