Benzazolides and their employment in phosphite ester oligonucleo

Details Benzazolides and their employment in phosphite ester oligonucleo Benzazolides and their employment in phosphite ester oligonucleo

1982-04-08

1984-10-02

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 536 29, C07H 1918, C07H 1920

Patent

active

044749481

ABSTRACT:
Benzotriazoles are employed in phosphite triester oligonucleotide synthesis. The benzotriazoles also form phosphinedibenzazolides. Processes employing these reagents are also disclosed.

REFERENCES:
patent: 3986967 (1976-10-01), Okorodudu
patent: 4174285 (1979-11-01), Braid
Cole, B. H., "Making Genes with Machines", High Technology, vol. 1, No. 1, 60-68.
Ogilvie, K. K. et al., Can. J. Chem., 58, 1389, 2686, (1980).
Ogilvie, K. K. et al., Tetrahedron Letters 21, 4159, (1980).
Caruthers, M. H. et al., Nucl. Acids Res., Symposium Series #7, 215, (1980).
Beaucage, S. L. et al., Tetrahedron Letters, 22, 1859, (1981).

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