Benzazepines, and their use as anthelminthics

Details Benzazepines, and their use as anthelminthics Benzazepines, and their use as anthelminthics

1984-07-13

1987-04-28

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514214, 540578, 540579, A61K 3155, C07D22300, C07D26708

Patent

active

046614893

ABSTRACT:
A compound of formula (I): ##STR1## in which R is optionally substituted phenyl; C.sub.3-8 cycloalkyl; C.sub.5-8 cycloalkenyl; C.sub.1-8 alkyl which may be straight or branched; C.sub.2-8 alkenyl which may be straight or branched; 5- or 6- membered heterocyclyl; or optionally substituted phenyl C.sub.1-4 alkyl, each of Y and Z, which may be the same or different, is oxygen or sulphur; and X is --CH.sub.2 -- or oxygen, a process for the preparation of such compounds and their use in human and veterinary medicine.

REFERENCES:
patent: 4001411 (1977-01-01), Seubert et al.
patent: 4162319 (1979-07-01), Seubert et al.
patent: 4497952 (1985-02-01), Kim et al.
patent: 4523013 (1985-06-01), Frehel et al.
Dixit et al., Indian Journal of Chemistry, vol. 14B, Nov. 1976, pp. 874-878.
Muller et al., Helvetica Chimica Acta, vol. 65, No. 7, (1982), pp. 2118-2132.
Hubert et al., Tetrahedron, vol. 31, pp. 1437-1441, (1975).
Andrews et al., "Medicinal Research Reviews, vol. 3, No. 2, pp. 147-200, (1983).

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