Benzazepines and related heterocyclic derivatives which are...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S593000

Reexamination Certificate

active

10450420

ABSTRACT:
The invention relates to novel benzazepines and related heterocyclic derivatives (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.

REFERENCES:
patent: 3236838 (1966-02-01), Archer et al.
patent: 3480714 (1969-11-01), Harvey
patent: WO 00/21951 (2000-04-01), None
Goff et al., 1995, “Solid-Phase Synthesis of Defined 1,4-Benzodiazepine-2,5-dione Mixtures,” J. Org. Chem. 60:5744-5745.

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