Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-03-21
1989-04-18
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540594, A61K 3133, C07D22316
Patent
active
048227935
ABSTRACT:
Compounds of the formula: ##STR1## or a salt thereof, wherein "Het" is a group of the formula: ##STR2## in which R.sup.1 is attached to position "a" or "b" of the benzene ring and R and R.sup.1, which are the same, are --NHSO.sub.2 (C.sub.1 -C.sub.4 alkyl), --NH.sub.2 or --NO.sub.2.
The compounds in which R and R.sup.1 are --NHSO.sub.2 (C.sub.1 -C.sub.4 alkyl) are cardiac antiarrhythmic agents. The compounds in which R and R.sup.1 are --NO.sub.2 and --NH.sub.2 are synthetic intermediates.
Arrowsmith John E.
Cross Peter E.
Akers Lawrence C.
Ginsburg Paul H.
Lee Mary C.
Pfizer Inc.
Richardson Peter C.
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