Benzamido-derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548567, A61K 3140, C07D20709

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active

047896833

ABSTRACT:
Novel therapeutically active compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom, a halogen atom, a cyano group, a lower alkyl group or an acyl group, R.sup.3 is a lower alkyl group; an alkenyl group; or a benzyl group optionally substituted with fluorine, chlorine, bromine, trifluoromethyl, lower alkyl or lower alkoxy, A.sup.1 and A.sup.2 are the same or different and each represents a hydrogen atom, a lower alkyl group, an acyl group, an alkoxycarbonyl group or a dialkylcarbamyl group, provided that when A.sup.1 and A.sup.2 are the same lower alkyl group and R.sup.3 is ethyl, R.sup.1 or R.sup.2 or both are selected among cyano, lower alkyl and acyl; or a physiologically acceptable salt or optical isomers thereof, methods for their preparation, pharmaceutical preparations containing the compounds and methods for their therapeutical use.

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C.A., 90:38696c (1979), Ogata et al.
Chemical Abstracts, vol. 86:14800g "Thermal Development-Type Diazo Copying Materials" (1977).
Banker et al., Modern Pharmaceutics (Date not available), pp. 565-566; Marcel Dekkar, Inc., N.Y. and Basal.
Pharmaceutics & Pharmacy Practice, Banker et al. (Date not available), p. 118; J. B. Lippincott Co., Philadelpia and Toronto.

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