Benzamides with local anaesthetic and antiarrhythmic activity, s

Details Benzamides with local anaesthetic and antiarrhythmic activity, s Benzamides with local anaesthetic and antiarrhythmic activity, s

1980-11-18

1981-12-15

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424267, 424274, 424324, 424310, 544165, 546234, 26032641, 564168, 560 37, A61K 31535, C07D26530, C07D21132, C07D20704

Patent

active

043059406

ABSTRACT:
Benzamides of formula I ##STR1## are described, in which R=CH.sub.3, Cl or COOCH.sub.3 ; R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals. CH.sub.2 R' is in position ortho, meta, or para with respect to the carbonyl group; and their salts thereof with pharmaceutically acceptable acids are described. The novel compounds exhibit local anaesthetic and antiarrhythmic activity.

REFERENCES:
patent: 2150190 (1940-03-01), Rossander et al.
patent: 2870146 (1959-01-01), Perron
patent: 3433833 (1969-03-01), Satzinger et al.
patent: 3950393 (1976-04-01), Keck et al.
patent: 3988371 (1976-10-01), Hansl
patent: 4097481 (1978-06-01), Banitt et al.
patent: 4158063 (1979-06-01), Hitzel et al.

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