Benzamide, heteroarylamide and reverse amides

Details Benzamide, heteroarylamide and reverse amides Benzamide, heteroarylamide and reverse amides

2007-05-08

2007-05-08

Balasubramanian, Venkataraman (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S182000

Reexamination Certificate

active

10292887

ABSTRACT:
The present invention relates to novel to P2X7inhibitors of formula Iand to processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are potent inhibitors of P2X7and as such are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.

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