Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-05-08
2007-05-08
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S182000
Reexamination Certificate
active
10292887
ABSTRACT:
The present invention relates to novel to P2X7inhibitors of formula Iand to processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them, and their use in therapy. The active compounds of the present invention are potent inhibitors of P2X7and as such are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
REFERENCES:
patent: 4594099 (1986-06-01), Yamada et al.
patent: 4766233 (1988-08-01), Lyga
patent: 4906286 (1990-03-01), Lyga
patent: 4906287 (1990-03-01), Lyga et al.
patent: 5077409 (1991-12-01), Wissner
patent: 5128351 (1992-07-01), Wissner
patent: 5691376 (1997-11-01), Caggiano et al.
patent: 5773646 (1998-06-01), Chandrakumar et al.
patent: 6020357 (2000-02-01), Pinto et al.
patent: 6180844 (2001-01-01), Fujita et al.
patent: 6187797 (2001-02-01), Pruitt et al.
patent: 6201024 (2001-03-01), Baxter et al.
patent: 6218376 (2001-04-01), Kindon et al.
patent: 6258838 (2001-07-01), Baxter et al.
patent: 6492355 (2002-12-01), Alcaraz et al.
patent: 2003/0144293 (2003-07-01), Duplantier et al.
patent: 2004/0180894 (2004-09-01), Dombroski et al.
patent: 2005/0009900 (2005-01-01), Dombroski et al.
patent: 2006/0018904 (2006-01-01), Chung et al.
patent: 2006/0040939 (2006-02-01), Dombroski et al.
patent: 0 077 938 (1983-05-01), None
patent: 0 514 339 (1992-11-01), None
patent: 0 563 384 (1993-10-01), None
patent: 0 688 773 (1995-12-01), None
patent: 877018 (1998-11-01), None
patent: 974576 (2000-01-01), None
patent: WO 86/00072 (1986-01-01), None
patent: WO 89/02891 (1989-04-01), None
patent: 9211242 (1992-07-01), None
patent: 9304686 (1993-03-01), None
patent: WO 95/22532 (1995-08-01), None
patent: 9527513 (1995-10-01), None
patent: 9538428 (1996-12-01), None
patent: 9722600 (1997-06-01), None
patent: 9723212 (1997-07-01), None
patent: 9828269 (1998-07-01), None
patent: 9842669 (1998-10-01), None
patent: 9843973 (1998-10-01), None
patent: 9917777 (1999-04-01), None
patent: 0027808 (1999-05-01), None
patent: 9929660 (1999-06-01), None
patent: 9929661 (1999-06-01), None
patent: 9929686 (1999-06-01), None
patent: 0017190 (2000-03-01), None
patent: 0035864 (2000-06-01), None
patent: 0061569 (2000-10-01), None
patent: 0071509 (2000-11-01), None
patent: 0071529 (2000-11-01), None
patent: 0123378 (2001-04-01), None
patent: 0128498 (2001-04-01), None
patent: 0142194 (2001-06-01), None
patent: 0144170 (2001-06-01), None
patent: 0144213 (2001-06-01), None
patent: 0146200 (2001-06-01), None
patent: 0158883 (2001-08-01), None
Dowd et al., British Journal of Pharmacology 125(2): 341-346, 1998.
West, Anthony R., Solid State Chemistry and its Applications, Wiley, New York, 1988, pp. 358 & 365.
Vippagunta et al., Advanced Drug Delivery Reviews 48: 3-26, 2001.
Theodoridis et al., “Synthesis and Structure-Activity Relationships of 1-Aryl-4-substituted-1,4-dihydro-5H-tetrazol-5-ones, a Novel Class of Pre- and Post-emergence Herbicides”, Pestic. Sci., 1990, 30, pp. 259-274.
Theodoridis et al., “Synthesis and Herbicidal Properties of Aryltriazolinones”, American Chemical Society, 1992 Chapter 14, pp. 134-146.
Lyga et al., “Synthesis, Herbicidal Actovity, and Action Mechanism of 2-Aryl-1,2,4-triazine-3,5-diones”, ACS 1991, Chapter 14, pp. 170-181.
Copending U.S. Appl. No. 10/748,342, filed Dec. 31, 2003.
Copending U.S. Appl. No. 60/583,851, filed Jun. 29, 2004.
Copending U.S. Appl. No. 60/583,813, filed Jun. 29, 2004.
Copending U.S. Appl. No. 60/669,756, filed Apr. 8, 2005.
Duplantier Allen J.
Subramanyam Chakrapani
Ashbrook Charles W.
Balasubramanian Venkataraman
Crissey Todd M.
Ginsburg Paul H.
Pfizer Inc.
LandOfFree
Benzamide, heteroarylamide and reverse amides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzamide, heteroarylamide and reverse amides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzamide, heteroarylamide and reverse amides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3810058