Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-01-31
2006-01-31
Solola, Taofiq (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S376000, C514S343000, C514S327000, C514S212030, C548S519000, C548S229000, C548S550000, C540S531000, C546S243000
Reexamination Certificate
active
06992103
ABSTRACT:
The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
REFERENCES:
patent: 5869024 (1999-02-01), Ranganathan
patent: 2004/0171881 (2004-09-01), John et al.
patent: 0 431/838 (1991-06-01), None
Faller Andrew
MacPherson David Timothy
Milner Peter Henry
Stanway Steven James
Trouw Leontine Saskia
Deppenbrock Bonnie L.
Freistein Andrew B.
SmithKline Beecham P.L.C.
Solola Taofiq
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