Benzamide derivatives, processes for their preparation, and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S376000, C514S343000, C514S327000, C514S212030, C548S519000, C548S229000, C548S550000, C540S531000, C546S243000

Reexamination Certificate

active

06992103

ABSTRACT:
The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.

REFERENCES:
patent: 5869024 (1999-02-01), Ranganathan
patent: 2004/0171881 (2004-09-01), John et al.
patent: 0 431/838 (1991-06-01), None

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