Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2010-03-23
2011-11-22
Anderson, Rebecca (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C546S171000, C548S338100, C548S510000, C549S494000, C564S156000, C514S398000, C514S423000, C514S426000, C514S461000, C514S613000
Reexamination Certificate
active
08063046
ABSTRACT:
Compounds having high angiogenesis inhibiting activity useful as agents for effective treatment and prevention of diseases involving pathologic angiogenesis, e.g. cancer and cancer metastasis, are of formula (II),where A1is C—X1or N; Q1is -A2=A3-, or a heteroatom selected from —O—, —S—, and —N(R10)—; Q2is -A4=A5-, or a heteroatom selected from —O—, —S—, and —N(R10)—; provided that Q1and Q2are not heteroatoms at the same time; A2is C—X2or N, A3is C—X3or N, A4is C—X4or N, and A5is C—X5or N; Y is C1-6alkyl, C3-9cycloalkyl, C2-7alkenyl, C2-7alkynyl, C1-6alkoxy, C2-7alkenyloxy, C2-7alkynyloxy, or C1-6alkylthio; Z is a hydrogen atom, hydroxy, C1-6alkyl, C3-9cycloalkyl, or —NR1R2; and L is selected from the formula:
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Asai Miyuki
Aso Kousuke
Hada Kihito
Hasegawa Masami
Koyano Hiroshi
Anderson Rebecca
Browdy and Neimark PLLC
Chugai Seiyaku Kabushiki Kaisha
Shterengarts Samantha
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