Benzamide derivative

Details Benzamide derivative Benzamide derivative

1994-11-28

1996-03-19

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142275, 5142388, 514331, 514428, 540610, 544 584, 544169, 546221, 546233, 548146, 548215, 548557, 548567, C07D21136, A61K 31445

Patent

active

055004229

ABSTRACT:
A benzamide derivative represented by the following formula: ##STR1## wherein R.sup.1 represents a hydrogen atom or a lower alkanoyl group; R.sup.2 represents a hydrogen atom or a halogen atom; R.sup.3 represents a lower alkoxy group; R.sup.4 represents a hydrogen atom or a lower alkyl group; R.sup.5 represents a hydrogen atom, a lower alkyl group, or a lower alkoxy group; A represents C.sub.1 -C.sub.7 alkylene group which may optionally be substituted with a lower alkyl group; X represents a methylene group, an oxygen atom, or a sulfur atom; m represents an integer of from 0 to 3; n represents an integer of from 0 to 3; and p represents an integer of from 0 to 2 and a pharmacologically acceptable salt thereof is provided. These compounds are useful since they have gastrointestinal stimulating activity, and a pharmaceutical composition comprising said compound is useful for the treatment of gastrointestinal diseases.

REFERENCES:
patent: 4163789 (1979-08-01), Mauri et al.
patent: 4808624 (1989-02-01), Monkovie et al.
patent: 4877780 (1989-10-01), Vega-Noverola et al.

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