Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1995-06-06
2000-01-18
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
424 185, 546247, 546229, 546233, 546184, 548566, 548568, 548400, A61K 5104, C07D21100, C07D20708
Patent
active
060155434
ABSTRACT:
The present invention relates to a class of compounds having affinity for certain cancer cells, e.g. lung carcinomas, colon carcinomas, renal carcinomas, prostate carcinomas, breast carcinomas, malignant melanomas, gliomas, neuroblastomas and pheochromocytomas. The compounds of the present invention can also bind with high specificity to cell surface sigma receptors and can therefore be used for diagnostic imaging of any tissue having an abundance of cells with sigma receptors. The present invention provides such compounds as agents for diagnostic imaging and for detecting and treating tumors containing the cancer cells described above.
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Baumgold Jesse
Bowen Wayne
John Christy S.
McAfee John G.
Moody Terry
Dees Jos,e G.
Hartley Michael G.
Research Corporation Technologies Inc.
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