Benz-1,2,3-oxathiazin-4(3F)-one-2,2-dioxides, a process for thei

Details Benz-1,2,3-oxathiazin-4(3F)-one-2,2-dioxides, a process for thei Benz-1,2,3-oxathiazin-4(3F)-one-2,2-dioxides, a process for thei

1995-03-13

1996-06-11

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D29100

Patent

active

055257291

ABSTRACT:
The invention relates to compounds of the formula (I) ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are, independently of one another, hydrogen, CF.sub.3, NO.sub.2, CN, halogen, --S(NSO.sub.2 CF.sub.3)CF.sub.3, (C.sub.1 -C.sub.4)-alkyl, phenyl, SO.sub.2 R.sup.5, COOR.sup.5, NR.sub.2.sup.5, where R.sup.5 is (C.sub.1 -C.sub.4)-alkyl, which can also be fluorinated, or phenyl, or R.sup.1 and R.sup.2, R.sup.2 and R.sup.3 or R.sup.3 and R.sup.4 together form an aliphatic or aromatic ring which can also contain an oxygen, sulfur or nitrogen atom.
The invention further provides a process for preparing the compounds of the formula (I), which comprises reacting compounds of the formula (II) ##STR2## where R.sup.1 to R.sup.4 are as defined above and X is hydrogen or an alkali metal, with elemental fluorine in the presence of an inert solvent and, if desired, an alkali metal fluoride at low temperatures.
The invention further provides for the use of the compounds of the formula (I) for the fluorination of compounds having carbanion character.

REFERENCES:
patent: 3780030 (1973-12-01), Morris
patent: 3926976 (1975-12-01), Clauss et al.
patent: 4018920 (1977-04-01), Chan
patent: 4479901 (1984-10-01), Barnette
patent: 4828764 (1989-05-01), DesMarteau
patent: 4900867 (1990-02-01), Wilkes et al.
patent: 5003074 (1991-03-01), Allmendinger et al.
patent: 5086178 (1992-02-01), Banks
patent: 5227493 (1993-07-01), Banks
patent: 5254732 (1993-10-01), Differding
Tetrahedron Letters, vol. 29, No. 29, No. 47, pp. 6087-6090, 1988.
Furin G. G., entitled "2. Some Electrophilic Fluorination Agents". In: New Fluorinating Agents in Organic Synthesis, pp. 35-68.
Journal of Synthetic Chemistry, Japan, vol. 50, No. 4, Apr. 1992, pp. 338-346 by Teruo Umemoto entitled "Recent Development of Fluorinating Agents".
The Journal of Organic Chemistry, vol. 57, No. 15, Jul. 17, 1992 by Resanti G & DesMarteau entitled "Electrophilic Fluorination of Pharmacologically Active 1,3-Dicarbonyl Compounds", pp. 4281-4284.
Angewandte Chemie, vol. 85, No. 22, Nov. 1973 entitled "Oxathiazinondioxide, eine neue Gruppe von Susstoffen" by Clauss et al., pp. 965-973.
Journal of Org. Chem., vol. 48, (1983), pp. 761-762.
Tetrahedron Letter, vol. 29, (1988), pp. 6087-6090.
Journal Chem. Soc. Perkin, Tans I, (1988), pp. 2805-2811.
Journal Am. Chem. Soc., vol. 1212 (1990), pp. 8563-8575.

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