Benoz-fused cycloalkane trans-1,2-diamine derivatives

Details Benoz-fused cycloalkane trans-1,2-diamine derivatives Benoz-fused cycloalkane trans-1,2-diamine derivatives

1987-07-16

1989-10-24

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514210, 514255, 514408, 514412, 514617, 5142352, 5142328, 514443, 514521, 514618, 514619, 514432, 514546, 544166, 544400, 548452, 548525, 548529, 548578, 548950, 564162, 564166, 564182, 564183, 564170, 549 58, 558414, 560 10, 560 13, A61K 3140, C07D29506

Patent

active

048762695

ABSTRACT:
Benzo-fused cycloalkane and oxa- and thia-cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy-1,2,3,4-tetra hydronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts of N-oxides thereof, are useful as analgesics and/or diuretics.

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patent: 4632935 (1986-12-01), Kaplan
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