Bengamide derivatives, process for preparing them, and their...

Details Bengamide derivatives, process for preparing them, and their... Bengamide derivatives, process for preparing them, and their...

2006-12-26

2006-12-26

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S526000, C540S527000

Reexamination Certificate

active

07153846

ABSTRACT:
The present invention relates to bengamide derivatives which are formed, during fermentation, by the microorganismMyxococcus virescensST200611 (DSM 15898), to their use for treating cancer diseases, to pharmaceuticals which comprise bengamide derivatives, to a process for preparing bengamides of the formula (V) and to the microorganismMyxococcus virescensST200611 (DSM 15898)

REFERENCES:
patent: 2004-262793 (2004-09-01), None
patent: WO 01/85697 (2001-11-01), None
Adamczeski et al. (Journal of the American Chemical Society (1989), 111(2), 647-654).
Groweiss, et al., Cytotoxic Metabolites from an Australian Collection of the Sponge, J. Nat. Prod.; 1999; 62; pp. 1691-1693.
Kinder, et al., Synthesis and Antitumor Activity of Ester-Modified Analogues of Bengamide B, J. Med. Chem.; 2001; 44; pp. 3691-3699.
Thale, et al., Bengamides Revisited: New Structures and Antitumor Studies, J. Org. Chem.; 2001; 66; pp. 1733-1741.

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