Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-12-26
2006-12-26
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S526000, C540S527000
Reexamination Certificate
active
07153846
ABSTRACT:
The present invention relates to bengamide derivatives which are formed, during fermentation, by the microorganismMyxococcus virescensST200611 (DSM 15898), to their use for treating cancer diseases, to pharmaceuticals which comprise bengamide derivatives, to a process for preparing bengamides of the formula (V) and to the microorganismMyxococcus virescensST200611 (DSM 15898)
REFERENCES:
patent: 2004-262793 (2004-09-01), None
patent: WO 01/85697 (2001-11-01), None
Adamczeski et al. (Journal of the American Chemical Society (1989), 111(2), 647-654).
Groweiss, et al., Cytotoxic Metabolites from an Australian Collection of the Sponge, J. Nat. Prod.; 1999; 62; pp. 1691-1693.
Kinder, et al., Synthesis and Antitumor Activity of Ester-Modified Analogues of Bengamide B, J. Med. Chem.; 2001; 44; pp. 3691-3699.
Thale, et al., Bengamides Revisited: New Structures and Antitumor Studies, J. Org. Chem.; 2001; 66; pp. 1733-1741.
Haag-Richter Sabine
Hoffmann Holger
Kurz Michael
Tietgen Heiko
Bolosak James
Kifle Bruck
Sanofi-Aventis Deutschland GmbH
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