Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...
Reexamination Certificate
2001-03-16
2008-07-29
Weber, Jon P (Department: 1657)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Solid support and method of culturing cells on said solid...
Reexamination Certificate
active
07405078
ABSTRACT:
By using a bed material for cell culture having a surface composed of two domains of domain A coated with a temperature-responsive polymer and domain B composed of any one or a combination of a domain coated with a polymer having high affinity with cells, a domain coated with the temperature-responsive polymer in an amount different from the amount of the temperature-responsive polymer of domain A, and a domain coated with a polymer which responds to a temperature different from the temperature to which domain A responds, a method for the co-culture of a plurality of kinds of cells which has heretofore been difficult becomes possible.
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Hirose et al, “(Temperature-Responsive Surface for Novel Co-Culture Systems of Hepatocytes with Endotelial Cells: 2-D Patterned and Double Layered Co-Cultures,” (Yonsei Medical Journal), 2000, vol. 41, No. 6, pp. 803-813.
Kikuchi Akihiko
Okano Teruo
Yamato Masayuki
Cellseed Inc.
Nixon & Vanderhye P.C.
Weber Jon P
Wood Amanda P
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