Beclomethasone dipropionate-hexane solvate and aerosols prepared

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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A61K 3156

Patent

active

042255970

ABSTRACT:
A beclomethasone dipropionate-hexane solvate, useful in the preparation of beclomethasone dipropionate aerosols is disclosed herein. The new n-hexane solvate is stable when stored as bulk, and convenient and cheap to prepare. The trichlorofluoromethane solvate prepared by contacting micronized n-hexane solvate with trichlorofluoromethane affords beclomethasone dipropionate-trichlorofluoromethane solvate which retains its small particle size.

REFERENCES:
patent: 3845085 (1974-10-01), Phillipps et al.
patent: 4044126 (1977-08-01), Cook et al.

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