Beazimidazole compounds active as inhibitors of the cholesterol

Details Beazimidazole compounds active as inhibitors of the cholesterol Beazimidazole compounds active as inhibitors of the cholesterol

1989-07-27

1990-07-10

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548329, 548332, 548333, C07D23518, C07D40706

Patent

active

049408003

ABSTRACT:
The compounds of formula ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 have the meanings given in the specification, are described.
The compounds of formula I are active as inhibitors of the enzyme HMG-CoA reductase and can be used in therapy as anti-hypercholesterolemics.

REFERENCES:
patent: 3915984 (1975-10-01), Gebert et al.
patent: 4434174 (1984-02-01), Diamond et al.
patent: 4714762 (1987-01-01), Hoefle et al.

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