Beat frequency ultrasonic microsphere contrast agent detection s

Surgery – Truss – Pad

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A61B 806

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active

056010869

ABSTRACT:
A system for and method of detecting and measuring concentrations of an ultrasonically-reflective microsphere contrast agent involving detecting non-linear sum and difference beat frequencies produced by the microspheres when two impinging signals with non-identical frequencies are combined by mixing. These beat frequencies can be used for a variety of applications such as detecting the presence of and measuring the flow rates of biological fluids and industrial liquids, including determining the concentration level of microspheres in the myocardium.

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Schrope et al, "Simulated capillary blood flow measurement using a nonlinear ultrasonic contrast agent", Ultrasonic Imaging, 14, (1992) pp. 134-158.

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