Bead for enantiomeric isomer resolution and process for...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C536S056000, C436S529000, C428S407000

Reexamination Certificate

active

07745616

ABSTRACT:
There is provided a process for producing beads for enantiomeric isomer resolution with a satisfactory separation efficiency. The beads for enantiomeric isomer resolution include a polysaccharide derivative, in which the polysaccharide derivative has a structure crosslinked at the 6-position hydroxy group of constituent units of the polysaccharide with a crosslinking agent. The process for producing the beads for enantiomeric isomer resolution includes: the step of adding dropwise an organic solvent solution of the polysaccharide derivative to a coagulation bath being stirred to thereby produce beads; the step of taking out the beads and then optionally drying the same after washing; and the step of reacting the beads with a crosslinking agent in an organic solvent to react at least part of the 6-position hydroxy groups in the constituent units of the polysaccharide with the crosslinking agent, thereby obtaining a reaction mixture containing beads having a crosslinked structure.

REFERENCES:
patent: 6217769 (2001-04-01), Okamoto et al.
patent: 7223334 (2007-05-01), Okamoto et al.
patent: 7323101 (2008-01-01), Okamoto et al.
patent: 7683167 (2010-03-01), Okamoto et al.
patent: 2006/0219615 (2006-10-01), Okamoto et al.
patent: A527235 (1992-09-01), None
patent: 03-261729 (1991-11-01), None
patent: 07-063622 (1995-07-01), None
patent: 8-59702 (1996-03-01), None
patent: WO03/004534 (2003-01-01), None
patent: WO 2004/086029 (2004-10-01), None

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