Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2008-03-04
2008-03-04
Wessendorf, T. D. (Department: 1639)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S005000, C435S004000, C435S091500, C435S091500, C536S023100, C536S001110
Reexamination Certificate
active
10828935
ABSTRACT:
The present invention includes composition and methods for making and using a combinatorial library having two or more beads, wherein attached to each bead is a unique nucleic acid aptamer that have disposed thereon a unique sequence. The library aptamers may be attached covalently to the one or more beads, which may be polystyrene beads. The aptamers may include phosphorothioate, phosphorodithioate and/or methylphosphonate linkages and may be single or double stranded DNA, RNA or even PNAs.
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Gorenstein David G.
Herzog Norbert
Luxon Bruce A.
Yang Xianbin
Board of Regents , The University of Texas System
Chalker Flores LLP
Flores Edwin
Wessendorf T. D.
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