Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-02-16
1990-12-11
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 82, 546 83, 546 84, 546153, 546156, 546159, 546162, 546164, 546169, 546170, 546178, 546171, C07D48704, A61K 31435, A61K 3147
Patent
active
049771604
ABSTRACT:
7- or 8-Substituted, partially hydrogenated pyrazolo[3,4-g]quinoline, thiazolo[4,5-g]quinoline, oxazolo[4,5-g]quinoline, and pyrrolo[3,4-g]quinoline derivatives, and 8- or 9-substituted, partially hydrogenated pyrido[2,3-g]quinazoline derivatives are D-2 dopamine agonists. 6-Oxo-1-substituted-octahydroquinolines and 6-oxo-1-substituted-decahydroquinolines which are additionally substituted in the 3- or 4-position are intermediates useful in preparation of the dopamine agonists. Acetals of 4,6-dioxo-1-substituted-decahydroquinoline 3-carboxylic acid esters enable synthesis of the foregoing compounds.
REFERENCES:
patent: 4198415 (1980-04-01), Kornfeld et al.
patent: 4230861 (1980-10-01), Kornfeld et al.
patent: 4235909 (1980-11-01), Bach et al.
patent: 4273932 (1981-06-01), Matsubara et al.
patent: 4468401 (1984-08-01), Hahn
patent: 4471121 (1984-09-01), Schaus et al.
patent: 4501890 (1985-02-01), Nichols et al.
patent: 4525584 (1985-06-01), Gallick-Whitaker
patent: 4537893 (1985-08-01), Titus et al.
patent: 4647667 (1987-03-01), Schaus
patent: 4659832 (1987-04-01), Schaus et al.
patent: 4778894 (1988-10-01), Schaus et al.
patent: 4826986 (1989-05-01), Huser et al.
Bach et al., J. Med. Chem., 23, 481 (1980).
Nordman et al., J. Med. Chem., 28(3), 367 (1985).
Huser Diane L.
Schaus John M.
Bernhardt E.
Eli Lilly and Company
Shah Mukund J.
Taylor Douglas J.
Whitaker Leroy
LandOfFree
BCD tricyclic ergoline part-structure analogues does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with BCD tricyclic ergoline part-structure analogues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and BCD tricyclic ergoline part-structure analogues will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-390451