Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-07-29
1998-04-28
Degen, Nancy
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435691, 435 914, 435325, 536 241, C12Q 168, C12P 2100, C12N 510, C07H 2104
Patent
active
057443106
ABSTRACT:
The present invention provides a substantially purified bax promoter and a nucleic acid molecule containing a nucleotide sequence encoding a gene product operably linked to a bax promoter. The invention also provides a substantially purified active fragment of a bax promoter and a nucleic acid molecule containing a nucleotide sequence encoding a gene product operably linked to an active fragment of a bax promoter. Cell-based screening assays for identifying an effective agent such as a drug that regulates the level of expression of a gene operably linked to a bax promoter, or an active fragment thereof, also are provided.
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Degen Nancy
Sandals William
The Burnham Institute
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