Basophil granule proteins

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530300, 530350, A61K 3802, C07K 200

Patent

active

054708257

ABSTRACT:
Several natural polypeptides (basophil granule proteins, "BGP") derived from the cytoplasmic granules of human basophils, and modified forms thereof, are described. These polypeptides, the DNA which encodes them and antibodies which recognize them, are useful as diagnostics for, and treatments for, pathologies involving inflammatory and IgE-mediated responses, parasitic and helminthic infections, hypersensitivity reactions and certain types of leukocytic leukemias.

REFERENCES:
patent: 4935370 (1990-06-01), Franke
Denburg et al., "Partial Separation and Functional Characterization of Guinea Pig Basophil-Stimulating Factor," Int. Arch. Allergy Appl. Immunol. (1986) 79(3):312-319.
Wasmoen et al, "Biochemical and Amino Acid Sequence Analysis of Human Eosinophil Granule Major Basic Protein," J. Biol. Chem. (1988) 263:12559-12561.
Geysen et al., "Use of Peptide Synthesis to Probe Viral Antigens for Epitopes to a Resolution of a Single Amino Acid," Proc. Natl. Acad. Sci. (USA) (1984) 81:3998-4002.
Stockinger et al. (1990) Blood 75:1820-1826.
Denburg et al. (1986) Biological Abstracts 81:Abst. 100863.
Dvorak et al. (1977) J. Immunology 119:38-46.
Ackerman et al. (1983) J. Exp. Med. 158:946-961.
Dvorak et al. (1989) Lab. Investigations 60:557-567.
Wasmoen et al. (1981) Proc. Nat. Acad. Sci., USA, 263: 12559-12561.
Blom et al. (1993) Scand. J. Immunol. 37:203-208.
Weller et al. (1984) J. Biol. Chem. 259: 15100-15105.
Abu-Ghazaleh (1992) J. Leucocyte Biol. 52:611-618.
Ackerman et al. (1993) J. Immunol. 150:465-468.
Durack et al. (1981) Proc. Nat. Acad. Sci., USA, 78:5165-5169.
Denburg et al. (1985) Blood 66:312-318.
Galli et al., Prog. Allergy (1984) 34:1-142.
Brown et al., J. Immunol. (1982) 129:790-796.
Ogilvie et al., Immunol. (1980) 39:385-389.
Juhlin et al., Lancet (1977) 1:1233-1235.
Schwartz et al., Immunological Diseases, Samter et al. (eds.), Little Brown & Co. 4th ed., pp. 157-201 (1988).
Solley et al., J. Clin. Invest. (1976) 58:408-420.
Charlesworth et al., J. Clin. Invest. (1989) 83:1519-1526.
Dvorak et al., J. Immunol. (1974) 113:1694-1702.
Orenstein et al., J. Immunol. (1978) 121:586-592.
Ackerman et al., J. Exp. Med. (1982) 155:1597-1609.
Castells et al., J. Immunol. (1987) 138:2184-2189.
Newball et al., J. Clin. Invest. (1979) 64:466-475.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Basophil granule proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Basophil granule proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Basophil granule proteins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2013685

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.