Basically substituted 3-sulfamoylbenzoic acid derivatives and pr

Details Basically substituted 3-sulfamoylbenzoic acid derivatives and pr Basically substituted 3-sulfamoylbenzoic acid derivatives and pr

1975-09-04

1977-06-14

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602471M, C07D41302, A61K 31535

Patent

active

040297870

ABSTRACT:
Antihypertensively-active 3-sulfamoyl-4-piperazinyl-benzoic acids, optionally substituted in the 2-position by halogen or alkyl, and the esters, amides, and nitriles of these acids are disclosed, as is a method for making these compounds by the reaction of the corresponding 4-halogeno- or 4-alkyl-(or 4-aryl-) sulfonyloxy-benzoic acids (or their esters etc.) with piperazines.

REFERENCES:
arya et al., J. Pharm. Sciences, vol. 58, No. 4, pp. 432-439, (1969).
Das et al., J. of Medicinal Chemistry, vol. 14, No. 9, pp. 890-891, (1971).
Tamayo et al., Chemical Abstracts, vol. 65, p. 13636e, (1966).

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