Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1989-01-24
1998-12-22
Kemmerer, Elizabeth C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
530350, C07K 1450
Patent
active
058521771
ABSTRACT:
A mutein of basic fibroblast growth factors (bFGF) possesses fibroblast growth promoting activity, growth stimulating activity of capillary endothelial cells and angiogenic activity, has high stability and is low toxicity. And therefore, the present mutein is advantageously used as a healing accelerator for burns etc., a therapeutic drug for thrombosis etc., and a cell cultivation promoter.
REFERENCES:
patent: 4956455 (1990-09-01), Esch et al.
patent: 4959314 (1990-09-01), Maik et al.
Senoo et al. Biochem. Biophys. Res. Commun. vol. 151, No. 2, pp. 701-708, 1988.
G. M. Fox et al. Journal of Biological Chemistry, vol. 263, No. 34, pp. 18452-18458, 1988.
Sommer, A., et al., Biochem. & Biophy. Res. Comm. 144, No. 2 1987.
Kurokawa et al. FEBS Lett. 213(1) pp. 189-194 (1987).
Eseh et al. Proc. Natl. Acad Sci USA 82:6507-6511 (1985).
Igarashi Koichi
Kurokawa Tsutomu
Sasada Reiko
Senoo Masaharu
Conlin David G.
Eisenstein Ronald I.
Kemmerer Elizabeth C.
Takeda Chemical Industries Ltd.
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