Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants – Aluminum compound containing
Patent
1993-07-27
1997-01-21
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Anti-perspirants or perspiration deodorants
Aluminum compound containing
423624, 424 65, 424682, A61K 738
Patent
active
055957293
ABSTRACT:
Disclosed are basic aluminum antiperspirant materials having univalent complex oxoanions (e.g., nitrate); methods of making such materials; antiperspirant compositions containing such basic aluminum materials, another antiperspirant active material (e.g., a basic zirconium halide salt), and optionally a neutral amino acid; and methods of making such compositions. Size exclusion high performance liquid chromatography chromatograms of the disclosed basic aluminum materials have a peak 4 relative area of at least 25%, a peak 3 relative area of less than 60%, the sum of the peaks 3 and 4 being at least 50%; and less than 10% of the chromatographic peaks eluting at peaks 1 and 2. The disclosed basic aluminum materials have less than 25% of the aluminum in the form of Al.sup.b polyhydroxyaquoaluminum, and have a .sup.27 Al NMR spectrum in which the area of the 71.5-73.5 ppm resonance line includes more than 50% of the combined areas of the 62.5-63.5 ppm and 71.5-73.5 ppm resonance lines, and 5%-30% of the total area under the spectrum from 140 ppm to -80 ppm is contained in the resonance line at 71.5-73.5 ppm. The basic aluminum material of the present invention can be produced by adding a stoichiometric or near-stoichiometric amount of aluminum metal to a solution of an aluminum salt having a univalent complex oxoanion; the basic aluminum material can also be made by adding to such solution of the aluminum salt, aluminum metal having, in total, a relatively small surface area (large-sized particles of aluminum).
REFERENCES:
patent: 2814584 (1957-11-01), Daley
patent: 3090728 (1963-05-01), Berger et al.
patent: 4331609 (1982-05-01), Orr
patent: 4539048 (1985-09-01), Cohen
patent: 4606915 (1986-08-01), Rosenberg et al.
patent: 4775528 (1988-10-01), Callaghan et al.
patent: 4859446 (1989-08-01), Abrutyn et al.
patent: 4871525 (1989-10-01), Giovanniello et al.
patent: 4900534 (1991-02-01), Inward
patent: 5202115 (1993-04-01), Vincenti et al.
Michniak, "Studies on the Mechanism of Topical Anhidrosis Due to Polyvalent Cations", International Journal of Cosmetic Science (1980), pp. 29-36.
Chem. Abstracts, vol. 103, No. 22 (2 Dec. 1985) p. 39.
Aluminum Chlorohydrate II: Physicochemical Properties, vol. 70, No. 7 (Jul. 1981).
Barr Morton L.
Vanderhoof Elaine L.
Vincenti Paul J.
Dodson Shelley A.
The Mennen Company
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