Base polymer for transdermal absorption preparation comprising a

Details Base polymer for transdermal absorption preparation comprising a Base polymer for transdermal absorption preparation comprising a

1997-06-30

1999-01-12

Brouillette, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424484, 424486, A61F 1300

Patent

active

058583955

ABSTRACT:
A base polymer for transdermal absorption preparation, which is a solid at ordinary temperatures, which becomes a liquid having a low viscosity near the skin temperature of human, which has heat-sensitive and water-sensitive properties as it has a hydrophilic segment, which is capable of stably storing the drug which conventionally has not been easily formulated into a transdermal absorption preparation, and which is capable of effecting transdermal absorption of the drug at a high releasing ratio and yet in a slow-releasing manner with less skin irritation. The base polymer comprises a heat-sensitive segment polyurethane which is represented by the following general formula:

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