Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2006-02-07
2006-02-07
Riley, Jezia (Department: 1637)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S006120, C435S091200, C536S022100, C536S023100, C536S024300, C536S025300
Reexamination Certificate
active
06994998
ABSTRACT:
The present invention relates to methods for the detection of polymorphisms by substituting a base-modified nucleotide for a natural nucleotide in a polynucleotide. The base-modified nucleotide renders the polynucleotide more susceptible to cleavage at the sites of its incorporation than site consisting of natural nucleotides. The fragments obtained are then analyzed to determine the presence or absence of a polymorphism.
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Allerson Charles
Kawate Tomohiko
Stanton, Jr. Vincent P.
Verdine Gregory L.
Wolfe Jia Liu
Riley Jezia
Sequenom Inc.
Squire Sanders & Dempsey L.L.P.
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