Base line correction method and apparatus

Details Base line correction method and apparatus Base line correction method and apparatus

1980-03-04

1982-11-02

Krass, Errol A.

Boots, shoes, and leggings

73 231, 364571, G01N 3108

Patent

active

043576680

ABSTRACT:
In a solvent gradient liquid chromatography system, base line shift is compensated by operating the system in a calibrate cycle with a desired solvent gradient program while subtracting and recording in digital form correction factors sufficient to maintain a flat base line at timed intervals during the program, and then successively recalling said digital correction factors at corresponding time intervals during a run cycle with a test sample and converting the correction factors to analog form and subtracting the converted correction factors from the system output signal for base line correction.

REFERENCES:
patent: 3475600 (1969-10-01), Spence
patent: 3506618 (1970-04-01), Smith
patent: 3634868 (1972-01-01), Pelavin et al.
patent: 3641444 (1972-02-01), Watts
patent: 3733474 (1973-05-01), Edwards et al.
patent: 3920970 (1975-11-01), Slaker
patent: 4043756 (1977-08-01), Sommervold
patent: 4099240 (1978-07-01), Rode et al.
patent: 4193039 (1980-03-01), Massa et al.
patent: 4216419 (1980-08-01), Van Dam et al.
Hendrickson et al.; "Design of a Microprocessor-Based Data System for Chromatography"; Lab; vol. 7, No. 9, Sep. 1975; pp. 100-107.

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