Base for ophthalmological medicinal preparations and on ophthalm

Details Base for ophthalmological medicinal preparations and on ophthalm Base for ophthalmological medicinal preparations and on ophthalm

1972-11-01

1976-01-27

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 16, 424 19, 424 22, 424 78, 128260, A61K 2712

Patent

active

039353036

ABSTRACT:
A base for ophthalmological medicinal preparations consists of a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and/or a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 percent acrylamide links.
The ophthalmological medicinal film is an oblong plate, 6-9 mm long, 3 - 5 mm wide and 0.2 - 0.6 mm thick, of the hompolymer and/or copolymer and an active medicinal ingredient, viz., 3-ethyl-4(1-methyl-5-imidazolyl)-tetrahydrofuran-2-one or atropine, or 3-methoxy-6-sulfanilam idopyridazine, or .beta.-dimethylamino-ethyl-p-butylaminobenzoate, or neamine, or 5-iodo-2-desoxyuridine.
The ophthalmological medicinal film is used for treatment of glaucoma of various forms, thrombosis of the central vein of the retina, atrophy of the optic nerve, for dilating the pupil and paralysis of accommodation in treatment of keratitis, iritis, iridocyclitis, ulcers of the cornea, trachoma, herpetic keratitis, uveitis and adenoviral infections, in extraction of foreign objects from the eye, and in various interventions in the organ of vision.

REFERENCES:
patent: 3025219 (1962-03-01), Maeder
patent: 3576760 (1971-04-01), Gould et al.
patent: 3577516 (1971-05-01), Gould et al.
patent: 3577518 (1971-05-01), Shepherd et al.
patent: 3641237 (1972-02-01), Gould et al.
patent: 3697643 (1972-10-01), Shepherd et al.
patent: 3775537 (1973-11-01), Lehman et al.

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