Bandpass reactive collision cell

Details Bandpass reactive collision cell Bandpass reactive collision cell

1998-05-29

2000-10-31

Berman, Jack

Radiant energy

Ionic separation or analysis

Methods

250292, H01J 4942

Patent

active

061406384

ABSTRACT:
A method of reducing isobaric interferences by transmitting ions from an ion source through an ion transmission device, typically a quadrupole collision cell, and then into an analyzing mass spectrometer, in which the collision cell is operated with a pass band which rejects intermediate ions which would otherwise tend to react to form isobaric interferences. Preferably ammonia is used as a reaction gas in the collision cell. Depending on the chemistry involved, the collision cell may be operated to set the low mass cutoff at an appropriate level, or more usually, the pass band will have both high and low mass cutoffs determined by applying both RF and DC to the collision cell. The collision cell may also be operated with a pass band to transmit ions into a time-of-flight (TOF) mass spectrometer, thus limiting the mass range of ions entering the TOF and thereby improving the duty cycle of the TOF.

REFERENCES:
patent: 3065640 (1962-11-01), Langmuir et al.
patent: 4234791 (1980-11-01), Engke et al.
patent: 4535235 (1985-08-01), McIver, Jr.
patent: 4540884 (1985-09-01), Stafford et al.
patent: 4963736 (1990-10-01), Douglas et al.
patent: 5187365 (1993-02-01), Kelley
patent: 5248875 (1993-09-01), Douglas et al.
patent: 5767512 (1998-06-01), Eiden et al.
patent: 5942752 (1999-08-01), Wang
Grahams et al., "Mass spectrometry/mass spectrometry", Chemical and Engineering News, Nov. 30, 1981, pp. 40-52.
Gerlich, Dieter, "Inhomogeneous RF Fields: A Versatile Tool for the Study of Processes with Slow Ions", State-Selected and State-to-State Ion-Molecule Reaction Dynamics, Part 1: Experiment, Edited by Cheuk-Yiu Ng and Michael Baer, Advances in Chemical Physics Series, vol. LXXXII, 1992.
Douglas, D.J., "Some Current Perspectives on ICP-MS", Canadian Journal of Spectroscopy, vol. 34, No.2, 1989.
Rowan and Houk, "Attenuation of Polyatomic Ion Interferences in Inductively Coupled Plasma Mass Spectrometry by Gas-Phase Collisions", Applied Spectroscopy, vol. 43, No. 6, 1989.
Koppenaal et al, "Performance of an Inductively Coupled Plasma Source Ion Trap Mass Spectrometer", Journal of Analytical Atomic Spectrometry, Sep. 1994, vol. 9, (1053-1058).
Eiden et al, "Selective Removal of Plasma Matrix Ions in Plasma Source Mass Spectrometry", Journal of Analytical Atomic Spectrometry, Apr. 1996, vol. 11 (317-322).
Ervin & Armentrout, "Translational energy dependence of . . . ", J. Chem. Phys. 83(1), Jul. 1, 1985.
Turner et al, "Interface Studies in the ICP-Mass Spectrometer", Plasma Source Mass Spectrometry: Developments and Applications, undated.
Douglas & French, "Collisional Focusing Effects in Radio Frequency Quadrupoles", J. Am.Soc. Mass Spectrom. 1992, 3, 398-408.
Barinaga & Koppenaal, "Ion-trap Mass Spectrometry with an Inductively Coupled Plasma Source", paper presented in part at the 41st ASMS Conference on Mass Spectrometry and Allied Topics, May 30-Jun. 4, 1993, San Francisco, CA.
Eiden et al, "Beneficial Ion/Molecule Reactions in Elemental Mass Spectrometry", presented in part at the Asilmor Conference on Mass Spectrometry), Sep. 1996 and 23rd Annual FACSS meeting, Kansas City, MO, Sep. 1996.
Douglas, D.J., "Applications of Collision Dynamics in Quadrupole Mass Spectrometry", J. Am. Soc. Mass Spectrom. 1998, 9, 101-113.
Authors: Watson, J. T., Jaouen, D., Mestdagh, H. and Rolando, C. International Journal of Mass Spectrometry and Ion Processes, 93 (1989) 225-235, Elsevier Science Publishers B.V., Amsterdam--Printed in the Netherlands "A Technique for Mass Selective Ion Rejection in a Quadrupole Reaction Chamber".

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